Innovation
By leveraging our Big Data expertise, we make your user data more meaningful and actionable.
INNOVATION
Work with nature, not against it.
Gutbiomics is the world’s most comprehensive platform for personalized nutrition and wellness. Our expert, automated engine drives you toward a customized treatment plan that leverages current research to find just what your body needs–whether it be supplements or lifestyle changes!
Overview
To measure is to know
“If you can’t measure it, you can’t improve it.”
Laboratory tests reveal who we really are – physically unique individuals, the sum of numerous biochemical systems. The study of these systems grants us perspective into how we live and how we feel. To know your body is to know yourself. With this knowledge we can make informed decisions on how to alter our habits to better our lives.
Each body is unique
Thus, current models of standardized treatment for everyone is not the proper way anymore. Instead, we promote the functional medicine view of healthcare as individualised and preventative, not just generalized and reactionary.
Sometimes, one size doesn't fit all
If you look at this from a training and development lens, it can sound pretty overwhelming. Which is why, at face value, a one-size-fits-all approach to training can be an attractive proposition. The idea that you can “build once, implement many” can save you a lot of time, resources, and implementation headaches. It is also likely to be less expensive in the short term. But in reality, we know that progressive training is ultimately about ensuring the best fit for the athlete, and when your training doesn’t differentiate, results are going to suffer. To maximize return on investment, personal development, and athlete satisfaction, coaches and staff must tailor professional development efforts to maximize the potential of each individual to optimizing athlete-performance which can lead to reduced fatigue and in turn can prevent injury risk.
Your genetics load the gun, but your lifestyle pulls the trigger.
Genetics is defined as the study of heredity and the variation of inherited characteristics. Microbiomics and metabolomics show, among other things, the effect of diet and lifestyle on the health of the human body and diversity of the intestinal and skin flora.
Part of the approach is a 360-degree diagnosis that combines results from saliva, stool and sweat. This can optionally be supplemented with analyses from blood and urine.
Put knowledge into practice
We recognize that successful treatment requires effective diagnosis. Thus, we strive to provide the most scientifically proven, accurate and reliable tests.
To help you get the most out of this report, here’s a quick multi-omics course. Once you’ve got an understanding of the basics, you’ll be all set to make the best use of your results and help apply them to make the lifestyle changes that are right for you.
Multi-omics approach
Multi-omics, is a biological analysis approach in which the data sets are multiple “omes”, such as the genome, epigenome, proteome, metabolome, and microbiome. The use of multiple omics technologies is to study life in a concerted way. By combining these “omes”, scientists can analyse complex biological big data to find associations between biological entities, pinpoint relevant biomarkers and build elaborate markers. In doing so, multi-omics integrates diverse omics data to find a coherently matching geno-pheno-envirotype relationship or association.
What is DNA?
DNA – also known as deoxyribonucleic acid – is an extremely long chain of molecules that contains the genetic blueprint of life on Earth. The DNA acts like a computer program – where the cell is the hardware and the DNA is the code. This code contains all the instructions that a living organism needs in order to grow, reproduce and function.
DNA is shaped like a ladder that’s been twisted to form what’s known as a double helix. The steps of the ladder are made of four nucleotides also known as bases: Adenine (A), Thymine (T), Cytosine (C), and Guanine (G).
There are many different types of cells in the human body, such as nerve cells, hair cells, heart cells, skin cells, and many more, all with different shapes and forms.
Genes are chemical instructions that tell a cell what job to perform. A gene is like a recipe for making a particular protein. Proteins do important jobs in every cell of the body.
Genes are written in code, with four chemicals (represented by the letters A, T, C, and G) that spell out the instructions to make a protein. People generally have two copies of most genes, one copy from each parent.
Most genes are made up of introns and exons. Exons are the parts of the gene that contain the information used to make a protein. They are the “coding” part of the gene. Introns are regions of DNA in between exons and do not code for proteins.
Your DNA is your own personal blueprint for life. The genome includes a person’s entire DNA, both the introns and the exons. The exome includes only the exons (the parts used to make proteins). The introns and other non-coding sequences of DNA are not part of the exome.
Single nucleotide polymorphisms (SNPs, pronounced ‘snips’):
SNP analysis focuses on differences in the DNA sequence at the single nucleotide level. They are the most common type of genetic variation among people.
In this multi-omics approach we focus on:
Genomics
focuses on identifying genetic variants associated with training methodology, sports psychology, and response to nutrition.
Epigenomics
focuses on the analysis of global epigenetic changes that provides important clues regarding mechanisms and function of gene regulation across many genes in a cell or organism.
Proteomics
is used to quantify peptide abundance, modification, and interaction.
Metabolomics
is the analysis of all metabolic products (metabolites) in a sample (saliva, sweat, stool,…). Metabolites are the intermediate and final products of all chemical reactions taking place in this sample. The complete set of metabolites is called a metabolome, also known as the chemical phenotype. It contains a wealth of information.
Microbiomics
All the microorganisms of a given community including human skin, mucosal surfaces, and the gut colonized by microorganisms, consisting of bacteria, viruses, and fungi, are investigated together.
Technologies
Understanding Genetic Variations
SNP analysis analyses the known genetic variants in a person’s DNA, in order to understand what makes individuals different from one another. These variants have been researched and analysed to show an effect. The focus lies only at the genes which have a direct impact on a pro-active response to changes in diet and exercise.
Understanding whole exome sequencing
There are several types of genetic tests. Some genetic tests “read” the genetic code of a single gene to see if that gene has any changes. Other genetic tests look for extra or missing pieces of DNA. Whole exome sequencing reads through the exons of most of the genes all at once.
Understanding microbiome metagenomics analysis versus 16S sequencing
Metagenomics, also known as shotgun sequencing, is the genetic analysis of microbial communities contained in samples ( stool, sweat and saliva). Shotgun sequencing offers the ability to simultaneously study non-bacterial microbes (e.g., fungi and viruses) alongside bacteria, but requires more sequencing labour. Alternatively, 16S sequencing can focus exclusively on one gene. In particular, 16S sequencing is useful for bacterial phylogeny and taxonomy investigations.
Understanding metabolomics mass spectrometry analysis
The field of metabolomics is a key discipline in the study of the metabolism of living organisms in a wide range of conditions, including health and disease. Liquid chromatography coupled with mass spectrometry (LC-MS) has become the most powerful analytical tool for screening and identification of metabolites in biological matrices.
An understanding of metabolism is pivotal to comprehending the phenotypic behaviour of all living organisms (including humans) where metabolism is integral to health and proper functioning. Metabolites are the intermediate products of metabolic reactions catalysed by various enzymes that naturally occur within cells.
Primary metabolites are synthesized by the cell because they are indispensable for their growth. Significant representatives are amino acids, alcohols, vitamins (B2 and B12), polyols, organic acids, as well as nucleotides (e.g. inosine-5′-monophosphate and guanosine-5′-monophosphate).
Secondary metabolites are compounds produced by an organism that are not required for primary metabolic processes, although they can have important other functions. They include medication, flavour, dye, pigments, pesticides and food additives.
Aritifical Intelligence (AI)
The Benefits of Intelligent Multi-Omics Analysis
Intelligent Multi-Omics Analysis provides you with unprecedented insights into your data. With this technology, you can gain a greater understanding of your data and uncover relationships and hidden patterns that can help you make better decisions and drive better outcomes. This technology also provides faster and more accurate analysis, allowing you to access actionable insights in less time.
Features
- Comprehensive Multi-Omics Analysis: Our AI/ML powered tool performs comprehensive analysis on omics data from proteomics, transcriptomics, metabolomics, and more to give you the most accurate insights into your system.
- Advanced Machine Learning Algorithms: Our platform is built with advanced machine learning algorithms to accurately recognize patterns in your data and generate meaningful results.
- Robust Data Visualization Capabilities: Our platform enables users to visualize their data in various formats such as bar graphs, heat maps, pie charts, etc., allowing them to gain more intuitive understanding of their data.
Benefits
- Superior Accuracy and Reliability: Our intelligent multi-omics analysis provides highly accurate and reliable insights into your system which are backed by our advanced ML algorithms that are constantly validated against real world data sets.
- Cost Savings & Time Savings: By utilizing our intelligent multi-omics analysis platform, you can save both time and money on costly lab experiments as our platform will provide insight into your system with much greater accuracy in a fraction of the time of traditional methods.
- Rapid Data Analysis: Using our advanced AI/ML powered tools allows you to quickly analyze large volumes of omics data so that you can make informed decisions faster than ever before.